GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10935120 | 1 | rs9834755 | chr3:134206845 | ANAPC13 | chr3:134196547-134204865:- | 0.5 | 8.06 | 9.6E-15 | Height |
| BLCA | cis | rs10935120 | 1 | rs9834755 | chr3:134206845 | CEP63 | chr3:134204575-134293852:+ | 0.25 | 4.39 | 1.49E-5 | Height |
| BLCA | cis | rs10935120 | 1 | rs9835204 | chr3:134261342 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.7 | 1.15E-13 | Height |
| BLCA | cis | rs10935120 | 1 | rs9835204 | chr3:134261342 | CEP63 | chr3:134204575-134293852:+ | 0.23 | 3.93 | 0.000102 | Height |
| BLCA | cis | rs1554120 | 1 | rs9836053 | chr3:150885877 | P2RY12 | chr3:151055238-151102544:- | 0.26 | 3.85 | 0.000138 | Heschl's gyrus morphology |
| BLCA | cis | rs12638253 | 1 | rs9837038 | chr3:156568469 | LEKR1 | chr3:156544076-156763918:+ | -0.24 | -4.65 | 4.62E-6 | Multiple sclerosis (severity) |
| BLCA | cis | rs9876781 | 1 | rs9838618 | chr3:48487353 | TREX1 | chr3:48501186-48509043:+ | -0.2 | -4.13 | 4.45E-5 | Longevity |
| BLCA | cis | rs9815354 | 1 | rs9838965 | chr3:41927938 | ULK4 | chr3:41288091-42003660:- | -0.63 | -9.83 | 1.72E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9839399 | chr3:41928044 | ULK4 | chr3:41288091-42003660:- | -0.63 | -9.83 | 1.72E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9840037 | chr3:41827522 | ULK4 | chr3:41288091-42003660:- | 0.63 | 9.72 | 4.22E-20 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9840532 | chr3:41885697 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.83 | 1.74E-20 | Diastolic blood pressure |
| BLCA | cis | rs10935120 | 1 | rs9841212 | chr3:134191938 | ANAPC13 | chr3:134196547-134204865:- | 0.45 | 7.15 | 4.56E-12 | Height |
| BLCA | cis | rs984222 | 1 | rs984222 | chr1:119503843 | WARS2 | chr1:119573841-119683295:- | -0.26 | -4.06 | 6.07E-5 | Waist-to-hip ratio adjusted for body mass index;Waist-hip ratio |
| BLCA | cis | rs9815354 | 1 | rs9842261 | chr3:41822708 | ULK4 | chr3:41288091-42003660:- | -0.54 | -7.72 | 1.02E-13 | Diastolic blood pressure |
| BLCA | cis | rs9815354 | 1 | rs9842305 | chr3:41998412 | ULK4 | chr3:41288091-42003660:- | -0.63 | -9.76 | 2.93E-20 | Diastolic blood pressure |